100000 - Document - Document and Entity Information
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100010 - Statement - Consolidated Balance Sheets
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100020 - Statement - Consolidated Balance Sheets (Parenthetical)
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100030 - Statement - Consolidated Statements of Operations
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100040 - Statement - Consolidated Statements of Operations (Parenthetical)
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100050 - Statement - Statement of Stockholders' Equity (Deflicit)
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100060 - Statement - Consolidated Statements of Cash Flows
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100070 - Statement - Statements of Cash Flows (Parenthetical)
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100080 - Disclosure - The Company
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100090 - Disclosure - Significant Accounting Policies
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100100 - Disclosure - Property and Equipment, Net
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100110 - Disclosure - Accrued Liabilities
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100120 - Disclosure - Royalty Purchase and Sale Agreement
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100130 - Disclosure - Long-Term Debt
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100140 - Disclosure - CARES Act Paycheck Protection Program Loan
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100150 - Disclosure - Preferred and Common Stock
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100160 - Disclosure - Common Stock Warrants
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100170 - Disclosure - Share-Based Compensation
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100180 - Disclosure - Income Taxes
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100190 - Disclosure - Commitment and Contingencies
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100200 - Disclosure - License and Other Agreements
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100210 - Disclosure - Fair Value Measurements
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100220 - Disclosure - Related Party Transactions
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100230 - Disclosure - Net Income (Loss) Per Share
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100240 - Disclosure - Significant Accounting Policies (Policies)
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100250 - Disclosure - Property and Equipment, Net (Tables)
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100260 - Disclosure - Accrued Liabilities (Tables)
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100270 - Disclosure - Royalty Purchase and Sale Agreement (Tables)
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100280 - Disclosure - Share-Based Compensation (Tables)
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100290 - Disclosure - Income Taxes (Tables)
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100300 - Disclosure - Commitment and Contingencies (Tables)
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100310 - Disclosure - Fair Value Measurements (Tables)
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100320 - Disclosure - Net Income (Loss) Per Share (Tables)
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100330 - Disclosure - The Company - Additional Information (Details)
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100340 - Disclosure - Significant Accounting Policies - Additional Information (Detail)
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100350 - Disclosure - Property and Equipment, Net - Schedule of Property and Equipment, Net (Details)
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100360 - Disclosure - Accrued Liabilities - Schedule of Accrued Liabilities (Details)
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100370 - Disclosure - Royalty Purchase and Sale Agreement (Additional Information) (Details)
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100380 - Disclosure - Royalty Purchase and Sale Agreement - Schedule of activity of the royalty obligation (Details)
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100390 - Disclosure - Long-Term Debt - Additional Information (Details)
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100400 - Disclosure - CARES Act Paycheck Protection Program Loan - Additional Information (Details)
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100410 - Disclosure - Preferred and Common Stock - Additional Information (Detail)
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100420 - Disclosure - Common Stock Warrants - Additional Information (Details)
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100430 - Disclosure - Share-Based Compensation - Additional Information (Details)
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100440 - Disclosure - Share-Based Compensation - Summary of Share-based Compensation Expense (Details)
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100450 - Disclosure - Share-Based Compensation - Weighted Average Assumptions Used in Black-Scholes Option Pricing Model to Calculate Fair Value of Underlying Common Stock (Details)
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100460 - Disclosure - Share-Based Compensation - Summary of Activity Related to Stock Options (Details)
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100470 - Disclosure - Share-Based Compensation - Additional Information about the Stock Option Outstanding and Exercisable (Details)
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100480 - Disclosure - Share-Based Compensation - Summary of the Activity Related to RSUs (Details)
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100490 - Disclosure - Income Taxes - Schedule of Net Deferred Tax Assets (Detail)
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100500 - Disclosure - Income Taxes - Schedule of Statutory and Effective Income Tax Rate Reconciliation (Detail)
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100510 - Disclosure - Income Taxes - Additional Information (Detail)
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100520 - Disclosure - Income Taxes - Summary of Activity Related to Uncertain Tax Positions (Detail)
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100530 - Disclosure - Commitment and Contingencies - Additional Information (Details)
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100540 - Disclosure - Commitment and Contingencies - Operating Leases Included on the Balance Sheet (Details)
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100550 - Disclosure - Commitment and Contingencies - Future Minimum Commitments Due Under Non-Cancelable Operating Leases (Details)
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100560 - Disclosure - Commitments and Contingencies - Summary of Annual Maintenance Fee Payments (Details)
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100570 - Disclosure - License and Other Agreements - Additional Information (Detail)
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100580 - Disclosure - Fair Value Measurements - Additional Information (Details)
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100590 - Disclosure - Fair Value Measurements - Summary of Assets and Liabilities Measured at Fair Value (Details)
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100600 - Disclosure - Related Party Transactions (Detail)
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100610 - Disclosure - Net Income (Loss) Per Share - Schedule of Earnings Per Share, Basic and Diluted (Details)
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100620 - Disclosure - Net Loss Per Share - Potential Common Stock Equivalents Excluded from Computation of Diluted Net Loss per Share (Details)
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Auditor Firm ID
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative
Document Transition Report
Document Transition Report
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Expected stock price volatility
Deferred Tax Assets, in Process Research and Development
Capitalized research and development expenses
Share-Based Payment Arrangement, Option, Exercise Price Range [Line Items]
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Unusual or Infrequent Items, or Both [Abstract]
Geographical [Axis]
Geographical
Effect of dilutive securities:
Earnings Per Share, Diluted, Other Disclosure [Abstract]
Effects of COVID-19.
Risks And Uncertainties Policy [Text Block]
Effects of COVID-19
Debt Instruments [Abstract]
Other non-current liabilities
Other Liabilities, Noncurrent
Accounts receivable, prepaid expenses and other current assets
Increase (Decrease) in Prepaid Expense and Other Assets, Total
Increase (Decrease) in Prepaid Expense and Other Assets
Restricted Stock Units (RSUs) [Member]
Restricted Stock Units (RSUs)
Global Net Product Sales Milestones
Global Net Product Sales Milestones
Fair Value, Inputs, Level 1 [Member]
Level 1
Entity Public Float
Entity Public Float
Increase (Decrease) in Other Operating Assets and Liabilities, Net, Total
Increase (Decrease) in Other Operating Assets and Liabilities, Net
Other assets and liabilities
Deferred tax liabilities depreciation differences.
Deferred Tax Liabilities Depreciation Differences
Depreciation differences
Payments on royalty purchase and sale agreement
Payments on royalty purchase and sale agreement
PaymentsToRoyaltyPurchaseAndSaleAgreement
PaymentsToRoyaltyPurchaseAndSaleAgreement
Unrecognized tax expenses.
Unrecognized Tax Expenses
Unrecognized tax expenses
Two Thousands And Sixteen Equity Incentive Plan [Member]
Two Thousands And Sixteen Equity Incentive Plan [Member]
2016 Equity Incentive Plan
Consideration received for territory expansion
Consideration for Territory Expansion Received
Consideration for territory expansion received.
Upfront payments.
Upfront Payments
Upfront payment
Fair Value Disclosures [Text Block]
Fair Value Measurements
Income Tax, Policy [Policy Text Block]
Income Taxes
Property, Plant and Equipment, Useful Life
Estimated Useful Lives (Years)
License and other revenue (includes $5,050 from a related party for the year ended December 31, 2023)
Revenue from Contract with Customer, Excluding Assessed Tax, Total
Revenue from Contract with Customer, Excluding Assessed Tax
Revenue
Line of credit facility remaining borrowing capacity not available for withdraw.
Line Of Credit Facility Remaining Borrowing Capacity Not Available For Withdraw
Line of credit facility remaining borrowing capacity not available for withdraw
Interest Expense, Borrowings, Total
Interest Expense, Borrowings
Interest expense on borrowings
ICFR Auditor Attestation Flag
Sales Agreement [Member]
Sales Agreement [Member]
Gain (Loss) on Termination of Lease
Gain on termination of operating lease
Gain on termination of operating lease
Compensation Related Costs, Policy [Policy Text Block]
Share-Based Compensation
REGENXBIO, Inc.
R E G E N X B I O Inc [Member]
REGENXBIO, Inc.
Title of Individual [Domain]
Debt instrument final payment percentage.
Debt Instrument Final Payment Percentage
Final payment during maturity, percentage
Other income
Other Nonoperating Income
Royalty Obligation
Royalty Obligation [Abstract]
Maximum proceeds from royalty purchase and sale agreement.
Maximum Proceeds from Royalty Purchase and Sale Agreement
Maximum proceeds from royalty purchase and sale agreement
Operating Lease, Liability, Noncurrent
Operating lease liabilities
Deferred Revenue Arrangement Type [Axis]
Deferred Revenue Arrangement Type
Assets, Fair Value Disclosure [Abstract]
Financial Assets:
Related Party Transactions [Abstract]
ESPP [Member]
ESPP [Member]
Assets, Current
Total current assets
Total liabilities and stockholders' (deficit) equity
Liabilities and Equity
Other expense
Other Nonoperating Expense
Other Nonoperating Expense, Total
Other expense
Entity Address, State or Province
Entity Address, State or Province
Operating loss carryforwards expiration period.
Operating Loss Carryforwards Expiration Period
Operating loss carryforwards expiration period
Long-Term Debt [Text Block]
Long-Term Debt
Issuance of common shares under private placement
Stock Issued During Period, Value, New Issues
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Number of Shares, Options outstanding, Ending balance
Number of Shares, Options outstanding, Beginning balance
Option to purchase common stock shares outstanding
Options Outstanding
Issuance of common shares under at-the-market sales agreement
Stock issued during period value at market sales agreement.
Stock Issued During Period Value At Market Sales Agreement
Range one.
Range One [Member]
$0.00 - $2.99
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted-average fair values granted
Trading Symbol
Trading Symbol
Common Stock, Shares, Issued, Total
Common Stock, Shares, Issued
Common stock, shares, issued
Stock issued during period shares follow on offering.
Stock Issued During Period Shares Follow On Offering
Issuance of common stock in follow-on offering, shares
Commercial Arrangement.
Commercial Arrangement [Member]
Commercial Arrangement
Research and development to Realted Party
Research and development to Realted Party
Research and development to Realted Party
Lease Expiration Date
Lease termination date
Schedule of Long-Term Debt Instruments [Table]
Debt Instrument [Table]
Shares, Outstanding
Ending balance, shares
Beginning balance, shares
Line of Credit Facility, Remaining Borrowing Capacity
Line of credit facility, remaining borrowing capacity
Common Stock, Capital Shares Reserved for Future Issuance
Shares common stock reserved for issuance
AOCI Attributable to Parent [Member]
Accumulated Other Comprehensive Loss
Long-term Debt, Current Maturities, Total
Long-Term Debt, Current Maturities
Current portion of long-term debt
Entity Address, City or Town
Entity Address, City or Town
Related Party Transaction [Line Items]
Related Party Transaction [Line Items]
Proceeds from registered direct offering, net of issuance costs
Net proceeds after deducting offering expenses.
Net Proceeds After Deducting Offering Expenses
Net proceeds after deducting offering expenses
Proceeds from registered direct offering, net of issuance costs
Lessee, Operating Lease, Renewal Term
Operating lease agreement renewal option term
Debt Disclosure [Text Block]
CARES Act Paycheck Protection Program Loan
Property, Plant and Equipment [Table Text Block]
Schedule of Property and Equipment, Net
Subsequent Event [Member]
Subsequent Event
Subsequent Event Type [Axis]
Subsequent Event Type
2026
Twenty Thousand Twenty Seven [ Member]
Twenty Thousand Twenty Seven [ Member]
2024
Lessee, Operating Lease, Liability, to be Paid, Next Rolling 12 Months
Third amended and restated loan and security agreement.
Third Amended And Restated Loan And Security Agreement [Member]
Third Amended And Restated Loan And Security Agreement
Unrecognized Tax Benefits, Increase Resulting from Prior Period Tax Positions
Gross increases - tax positions in prior period
Chief Executive Officer [Member]
Additional Paid-in Capital [Member]
Additional Paid-In-Capital
Royalty Sub Member [Member]
Royalty Sub Member [Member]
Property, Plant, and Equipment, Useful Life, Term, Description [Extensible Enumeration]
Liabilities, Current [Abstract]
Current liabilities:
Assets, Current [Abstract]
Current assets:
Counterparty Name [Axis]
Counterparty Name
Preferred Stock, Par or Stated Value Per Share
Preferred stock, par value
Base annual rental income fixed percentage increase.
Base Annual Rental Income Fixed Percentage Increase
Percentage of increase per year
Statement of Stockholders' Equity [Abstract]
Option fee paid.
Option Fee Paid
Option fee paid
Common stock fair market value per share.
Common Stock Fair Market Value Per Share
Fair market value per share of common stock
Operating Lease, Liability, Current
Current portion of operating lease liabilities
Lender Name [Axis]
Lender Name
Debt Instrument, Maturity Date
Note, Maturity date
Loans held-for-sale, maturity date
Up-front Payment Arrangement [Member]
Upfront payment
Long-term Debt, Total
Long-Term Debt
Long term debt
Property, Plant and Equipment, Net, Ending Balance
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net
Property and equipment, net
Property and equipment, net
Deferred Tax Assets, Operating Losses Carryforwards, Domestic
Deferred Tax Assets, Operating Losses Carryforwards, Domestic
Deferred tax Federal Net Operating Carry forward
Bausch health ireland limited (Bausch).
Bausch Health Ireland Limited [Member]
Bausch Health Ireland Limited
Bausch
Income tax disclosure line items.
Income Tax Disclosure [Line Items]
Income Tax Disclosure [Line Items]
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
U.S. federal tax rate
Royalty Purchase and Sales Agreement
Royalty Purchase and Sales Agreement [Abstract]
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Entity Central Index Key
Entity Central Index Key
Accretion of deferred closing costs.
Accretion Of Deferred Closing Costs
Accretion of deferred closing costs
Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures, Total
Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures
Vesting and settlement of restricted stock units
Silicon Valley Bank.
Silicon Valley Bank [Member]
Silicon Valley Bank
Plan Name [Domain]
Plan Name
Restricted cash money market.
Restricted Cash Money Market [Member]
Restricted Cash Money Market
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Outstanding, Weighted Average Remaining Contractual Terms
Weighted average remaining life of warrants
Assets, Fair Value Disclosure
Total financial assets
Assets, Fair Value Disclosure, Total
Lessee, Operating Lease, Option to Extend
Lessee, operating lease, option to extend, description
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding
Preferred stock, shares outstanding
Common stock, shares outstanding
Stock issued during period value follow on offering.
Stock Issued During Period Value Follow On Offering
Issuance of common shares under follow-on offering
Reconciliation of cash, cash equivalents and restricted cash:
Reconciliation of cash, cash equivalents and restricted cash.
Reconciliation Of Cash Cash Equivalents And Restricted Cash [Abstract]
Liabilities, Current
Total current liabilities
Entity Tax Identification Number
Entity Tax Identification Number
Range three.
Range Three [Member]
$7.00 - $8.99
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities:
Financial Instruments [Domain]
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost
Stock compensation expense
Award Date [Domain]
Stock Issued During Period, Value, Employee Stock Purchase Plan
Issuance of common shares under employee stock purchase plan
Award Type [Axis]
Award Type
Accounts Payable And Accrued Liabilities To A Related party
Accounts Payable And Accrued Liabilities To A Related party
Accounts Payable And Accrued Liabilities To A Related party
Restricted Stock [Member]
Class of Warrant or Right [Line Items]
Class Of Warrant Or Right [Line Items]
2028
Twenty Thousand Twenty Eight1 [Member]
Twenty Thousand Twenty Eight1 [Member]
Cowen and company llc.
Cowen And Company L L C [Member]
Cowen and Company LLC
Plan Name [Axis]
Plan Name
Proceeds from option fee previously received.
Proceeds From Option Fee Previously Received
Proceeds from option fee previously received
Geographical [Domain]
Geographical
Lessee, Operating Lease, Term of Contract
Operating lease agreement term
Deferred tax assets tax non deductible accruals accrued expenses.
Deferred Tax Assets Tax Non Deductible Accruals Accrued Expenses
Non-deductible accrued expenses
Assets
Total assets
Utilities Operating Expense, Maintenance
Operating Lease, Right-of-Use Asset
Operating lease right-of-use asset
Range four.
Range Four [Member]
$9.00 - $20.84
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Unrecognized compensation expense related to unvested stock options
Eligible payroll costs.
Eligible Payroll Costs
Eligible Payroll Costs
Entity Registrant Name
Entity Registrant Name
Retained Earnings (Accumulated Deficit), Ending Balance
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Total
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Purchase of property and equipment in accounts payable and accrued liabilities
Purchase of property and equipment included in accrued liabilities
Purchase of property and equipment included in accrued liabilities
Supplemental Cash Flow Information [Abstract]
Supplemental disclosure
Retained Earnings [Member]
Accumulated Deficit
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Non-vested units outstanding, Number of Shares, Ending balance
Non-vested units outstanding, Number of Shares, Beginning balance
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Issuance of common shares under employee stock purchase plan, shares
Common stock purchased
Minimum [Member]
Minimum
Loan, Securitized or Asset-Backed Financing Arrangement, Principal Outstanding
Aggregate principal amount
Proceeds from Stock Options Exercised
Proceeds from exercise of stock options
Significant Accounting Policies [Text Block]
Significant Accounting Policies
Operating Lease, Liability
Total operating lease liabilities
Total operating lease liabilities
Commitment and Contingencies [Line Items].
Commitment And Contingencies [Line Items]
Commitment And Contingencies [Line Items]
Interest expense on borrowings
Debt Instrument, Decrease, Forgiveness
Equity Component [Domain]
Equity Component
Employee Stock Option [Member]
Outstanding Stock Options
Stock Options
Common stock warrants.
Common Stock Warrants [Member]
Convertible Stock Warrant
Forgiveness of PPP Loan and accrued interest
Forgiveness of Paycheck Protection Program loan and accrued interest.
Forgiveness Of Paycheck Protection Program Loan And Accrued Interest
Operating Loss Carryforwards [Table]
Operating Loss Carryforwards [Table]
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Adjustments to reconcile net (loss) income to net cash used inoperating activities:
Debt Disclosure [Abstract]
Issuance of common shares under a direct registered offering
Issuance of common shares value under a direct registered offering
Issuance of common shares value under a direct registered offering
PPP Loan [Member]
PPP Loan [Member]
Debt Instrument, Basis Spread on Variable Rate
Variable interest rate
Entity Current Reporting Status
Entity Current Reporting Status
Additional milestone payment.
Additional Milestone Payment
Additional milestone payments
Common Stock, Shares Authorized
Common stock, shares authorized
Research and development (includes $1,109 to a related party for the year ended December 31, 2023)
Research and Development Expense, Total
Research and Development Expense
Accrued liabilities to a related party
Accrued liabilities current related party
Accrued liabilities current related party
Debt, Policy [Policy Text Block]
Debt Discount
Common stock warrants abstract.
Common Stock Warrants [Abstract]
XIPERE member
XIPERE [Member]
Schedule of activity of purchase and sale agreement.
Schedule of Activity of Purchase and Sale Agreement [Table Text Block]
Schedule of activity of the royalty obligation
Assets [Abstract]
Assets
Revenue from Contract with Customer [Policy Text Block]
Revenue Recognition
Share-Based Payment Arrangement, Option, Exercise Price Range [Table]
Schedule Of Share Based Compensation Shares Authorized Under Stock Option Plans By Exercise Price Range [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Shares available for future grant
At The Market Sales Agreement.
At The Market Sales Agreement Member
At-the-market Sales Agreement
Common stock, $0.001 par value; 200,000,000 shares authorized at December 31, 2023 and 2022, respectively; 62,850,841 and 59,722,930 shares issued and outstanding at December 31, 2023 and 2022, respectively
Common Stock, Value, Issued, Ending Balance
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Total
Common Stock, Value, Issued
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Valuation allowance
Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block]
Accrued Liabilities
Furniture and Fixtures [Member]
Furniture and Fixtures
Accrued Expense
Accrued liabilities (includes $215 to a related party as of December 31, 2023)
Accrued Liabilities, Current
Accrued liabilities, current
Current Fiscal Year End Date
Current Fiscal Year End Date
Cash and money markets.
Cash And Money Markets [Member]
Cash and Money Markets
Share-based Payment Arrangement, Noncash Expense, Total
Share-Based Payment Arrangement, Noncash Expense
Share-based compensation expense
Auditor Name
Proceeds, Issuance of Shares, Share-Based Payment Arrangement, Excluding Option Exercised
Proceeds from shares issued under employee stock purchase plan
Operating Income (Loss)
Loss from operations
Repayments of Debt
Repayment of outstanding amount under the loan agreement including fees
Entity Ex Transition Period
Entity Ex Transition Period
Tax Period [Axis]
Tax Period
Share-Based Payment Arrangement, Option, Exercise Price Range, Outstanding, Weighted Average Remaining Contractual Term
Weighted Average Remaining Contractual Life (Years)
Research and Development Expense [Member]
Research and Development
Maintenance Fee Due 2025
2025
Maintenance Fee Payments Due In Rolling Year Two
Maintenance Fee Payments Due In Rolling Year Two
Gross decreases - tax positions in prior period
Gross decreases - tax positions in prior period
Unrecognized Tax Benefits, Decrease Resulting from Prior Period Tax Positions
Share-Based Payment Arrangement, Expense
Share-based compensation expense
Minimum Sales To Applied Highest Royalty Rate
Minimum Sales To Applied Highest Royalty Rate
Paycheck protection program.
Paycheck Protection Program [Member]
PPP Loan
Milestone payments.
Milestone Payments
Milestone payments
Maintenance Fee Due 2028
Maintenance Fee Operating License Liability Payments Due Year Five
Maintenance Fee Operating License Liability Payments Due Year Five
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Aggregate Intrinsic Value
REGENXBIO, Inc.[Member]
REGENXBIO, Inc. member.
REGENXBIO
License [Member]
License [Member]
License [Member]
Liability related to sales of future royalties and non cash interest expense.
Liability Related to Sales of Future Royalties and Non Cash Interest Expense [Policy Text Block]
Liability Related to the Sales of Future Royalties and Non-Cash Interest Expense
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Maintenance Fee Due 2026
2026
Maintenance Fee Payments Due In Rolling Year Three
Maintenance Fee Payments Due In Rolling Year Three
Effective Income Tax Rate Reconciliation, Tax Credit, Percent, Total
Effective Income Tax Rate Reconciliation, Tax Credit, Percent
Tax credit
License and other agreement.
License And Other Agreement [Abstract]
Operating Expenses [Abstract]
Operating expenses:
Property, Plant and Equipment [Abstract]
Entity Voluntary Filers
Entity Voluntary Filers
Aggregate milestone payments from the licensees
Proceeds from License Fees Received
2011 Stock Incentive Plan, 2016 Equity Incentive Plan
Two Thousands And Eleven Stock Incentive Plan Two Thousands And Sixteen Equity Incentive Plan [Member]
Two thousands and eleven stock incentive plan two thousands and sixteen equity incentive plan.
Commitments and Contingencies Disclosure [Abstract]
Other assets
Other Assets, Noncurrent
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Number of shares grants
Number of Shares, Granted
Other Accrued Liabilities, Current
Accrued expense
BioCryst
BioCryst Pharmaceuticals, Inc [Member]
BioCryst Pharmaceuticals, Inc [Member]
Equity [Text Block]
Preferred and Common Stock
Depreciation, Total
Depreciation
Depreciation
Interest Paid, Excluding Capitalized Interest, Operating Activities
Interest paid
Second Amended and Restated Loan and Security Agreement, Initial Tranche
Second amended and restated loan and security agreement, first tranche.
Second Amended And Restated Loan And Security Agreement First Tranche [Member]
Second Amended and Restated Loan and Security Agreement, Initial Tranche
Share-Based Compensation Arrangement by Share-Based Payment Award, Description
Share based compensation arrangement description
Additional Paid in Capital, Ending Balance
Additional Paid in Capital, Beginning Balance
Additional Paid in Capital, Total
Additional Paid in Capital
Additional paid-in capital
Liabilities [Abstract]
Liabilities
Stockholders' (deficit) equity:
Equity, Attributable to Parent [Abstract]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Gain (Loss) on Disposition of Property Plant Equipment, Total
Gain (Loss) on Disposition of Property Plant Equipment
Loss on disposal of fixed assets
Line of Credit Facility, Maximum Borrowing Capacity
Line of credit facility, maximum borrowing capacity
2016 Plan.
Two Thousand Sixteen Equity Incentive Plan [Member]
2016 Stock Incentive Plan
Cost of goods sold
Cost of Goods and Services Sold
Cost of Goods and Services Sold, Total
Earnings Per Share [Abstract]
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Future Minimum Commitments Due Under Non-Cancelable Operating Leases
Accounting Policies [Abstract]
Other agreement.
Other Agreement [Member]
Other Agreement
Non cash interest expense on liability related to sales of future royalties.
Non Cash Interest Expense on Liability Related to Sales of Future Royalties
Non-cash interest expense on liability related to the sales of future royalties
Non-cash interest expense on liability related to the sales of future royalties
Maintenance Fee Due 2026
Maintenance Fee Operating License Liability Payments Due Year Three
Maintenance Fee Operating License Liability Payments Due Year Three
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Concentration of Credit Risk Arising From Cash Deposits in Excess of Insured Limits
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Debt Instrument, Interest Rate, Effective Percentage
Effective interest rate
Royalty Purchase And Sale Agreement Issuance Costs
Royalty Purchase And Sale Agreement Issuance Costs
Proceeds from royalty purchase and sale agreement
Earnings Per Share, Basic
Earnings Per Share, Basic, Total
Net (loss) income per share of common stock - basic
Commitments and Contingencies
Commitments and contingencies
Income Statement [Abstract]
Property, Plant and Equipment Disclosure [Text Block]
Property and Equipment, Net
Accounts payable and accrued liabilities (includes $82 to a related party for the year ended December 31, 2023)
Increase (Decrease) in Accounts Payable and Accrued Liabilities, Total
Increase (Decrease) in Accounts Payable and Accrued Liabilities
Operating Lease, Cost
Operating Lease, Cost
Short-Term Lease, Cost
Short-term Lease, Cost
Final payment.
Final Payment [Member]
Final Payment
Statistical Measurement [Domain]
Statistical Measurement
Net Cash Provided by (Used in) Operating Activities
Net cash used in operating activities
Fair value assets between level 1 level 2 and level 3 transfers amount.
Fair Value Assets Between Level1 Level2 And Level3 Transfers Amount
Significant transfers between Levels 1, 2 and 3
Balance at December 31, 2022
Initial proceeds from royalty purchase and sale agreement.
Initial Proceeds from Royalty Purchase and Sale Agreement
Initial proceeds from royalty purchase and sale agreement
All Award Types
Award Type
Document Period End Date
Document Period End Date
Statistical Measurement [Axis]
Statistical Measurement
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
Operating Lease, Payments
Operating lease liabilities
Purchase and Sale Agreement Description
Purchase and Sale Agreement Description
Purchase and sale agreement description
Earnings Per Share, Diluted
Earnings Per Share, Diluted, Total
Net (loss) income per share of common stock - diluted
Product and Service [Domain]
Product and Service
Operating Loss Carryforwards, Limitations on Use
Operating loss carryforwards, limitations on use
Deferred Tax Assets, Operating Loss Carryforwards, Total
Deferred Tax Assets, Operating Loss Carryforwards
Net operating loss carryforwards
Deferred tax assets, net operating loss carryforwards
Unrecognized Tax Benefits
Balance of uncertain tax positions at the end of the year
Balance of uncertain tax positions at the beginning of the year
Common stock warrants disclosure.
Common Stock Warrants Disclosure [Text Block]
Common Stock Warrants
Asset Acquisition [Axis]
Debt Instrument, Name [Domain]
Debt Instrument, Name
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV
Share-Based Payment Arrangement, Option, Exercise Price Range, Exercisable, Weighted Average Remaining Contractual Term
Weighted Average Remaining Contractual Life (Years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Number of Shares, Options exercisable
Options Exercisable
Operating Loss Carryforwards [Line Items]
Operating Loss Carryforwards [Line Items]
Accounts payable current related party
Accounts Payable Related Party Current
Accounts Payable Related Party Current
Payments on royalty purchase and sale agreement
Payments on royalty purchase and sale agreement
Debt Related Commitment Fees and Debt Issuance Costs
Royalty purchased
Issuance costs
Royalty Purchase and Sale Agreement
Royalty Purchase and Sale Agreement [Member]
Royalty Purchase And Sale Agreement
Accretion of final payment of amount borrowed.
Accretion Of Final Payment Of Amount Borrowed
Accretion of scheduled final payment
Incremental borrowing rate.
Incremental Borrowing Rate
Incremental borrowing rate
Addition of common stock shares reserved for future issuance.
Addition Of Common Stock Shares Reserved For Future Issuance
Addition of common stock shares reserved for future issuance
Net deferred tax asset
Deferred Tax Assets, Net
Net deferred tax asset
Components of Deferred Tax Assets and Liabilities [Abstract]
Deferred tax asset (liability)
Two thousands and sixteen employee stock purchase plan.
Two Thousands And Sixteen Employee Stock Purchase Plan [Member]
2016 Employee Stock Purchase Plan
Sales-based milestone payments
Sales-Based Milestone Payments
Sales-based milestone payments
Finite-Lived Intangible Assets, Major Class Name [Domain]
Two thousand sixteen employee stock purchase plan.
Two Thousand Sixteen Employee Stock Purchase Plan [Member]
2016 Employee Stock Purchase Plan
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Exercise of stock options, shares
Number of Shares, Exercised
Permanent difference
Effective Income Tax Rate Reconciliation, Other Adjustments, Percent
Liabilities and Equity [Abstract]
Liabilities and stockholders’ equity
Maintenance Fee Due 2024
Maintenance Fee Operating License Liability Payments Due Next Twelve Months
Maintenance Fee Operating License Liability Payments Due Next Twelve Months
Accrued research and development expenses.
Accrued Research And Development Expenses
Accrued research and development
Silicon Valley Bank, MidCap funding XII trust and MidCap financial trust.
Silicon Valley Bank Mid Cap Funding X I I Trust And Mid Cap Financial Trust [Member]
Silicon Valley Bank , MidCap Funding XII Trust and MidCap Financial Trust
Proceeds from registered direct offering net of issuance costs
Proceeds from registered direct offering net of issuance costs
Proceeds from registered direct offering, net of issuance costs
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Entity Interactive Data Current
Entity Interactive Data Current
Private Placement [Member]
Private Placement
Registered Direct Offering
Unrecognized Tax Benefits that Would Impact Effective Tax Rate
Unrecognized tax benefits that would affect the effective tax rate if recognized
Type of Revenue [Extensible List]
Revenue, Product and Service [Extensible Enumeration]
Credit Facility [Domain]
Credit Facility
Equity [Abstract]
Schedule of Short-Term Debt [Table]
Schedule Of Short Term Debt [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Number of Shares, Granted
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Upfront License Fee
Upfront License Fee
Debt Instrument, Payment Terms
Debt instrument, payment terms
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Weighted Average Exercise Price, Exercised
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash Equivalents
Debt related commitment fees and debt related issuance costs.
Debt Related Commitment Fees and Debt Related Issuance Costs
Debt related commitment fees and debt related issuance costs
License Arrangement member.
License Arrangement [Member]
License Arrangement
Equity Components [Axis]
Equity Components
Net proceeds from issuance of stock.
Net Proceeds From Issuance Of Stock
Net proceeds from issuance of stock
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Vested
Local Phone Number
Local Phone Number
Property, Plant and Equipment [Line Items]
Property Plant And Equipment [Line Items]
Sale of Stock [Axis]
Sale of Stock
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Weighted Average Exercise Price, Options exercisable
Weighted Average Exercise Price
Deferred revenue
Increase (Decrease) in Deferred Revenue
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures, Total
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures
Vesting and settlement of restricted stock units, shares
accounts payable and accrued liabilities
Increase (Decrease) in Other Accounts Payable and Accrued Liabilities
Statement of Cash Flows [Abstract]
Board of Directors [Member]
Director [Member]
Earliest Tax Year [Member]
Earliest Tax Year
Income Tax Authority [Domain]
Income Tax Authority
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Property, Plant and Equipment, Policy [Policy Text Block]
Property and Equipment, Net
Document Annual Report
Document Annual Report
Common Stock, Par or Stated Value Per Share
Common stock, par value
License and other agreements disclosure.
License And Other Agreements Disclosure [Text Block]
License and Other Agreements
Initial proceeds from royalty purchase and sales agreement.
Initial Proceeds From Royalty Purchase and Sales Agreement
Initial proceeds from royalty purchase and sales agreement
Debt Instrument, Interest Rate, Stated Percentage
Fixed interest rate
Cumulative Effect, Period of Adoption [Axis]
Cumulative Effect, Period of Adoption
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Expected to be recognized over a weighted average period
Long-Lived Tangible Asset [Axis]
Long-Lived Tangible Asset
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Maximum [Member]
Maximum [Member]
Threshold percentage of sales for tiered royalties.
Threshold Percentage Of Sales For Tiered Royalties
Threshold percentage of sales for tiered royalties
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
The Company
Accrued interest
Debt Instrument, Increase, Accrued Interest
Fair Value, Inputs, Level 3 [Member]
Level 3
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Share-based compensation expense
Fair Value, Recurring and Nonrecurring [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Research And Development Arrangement Contract To Perform For Others [Line Items]
Net (decrease) increase in cash, cash equivalents and restricted cash
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
Payables and Accruals [Abstract]
Work in process [Member]
Work in process [Member]
Work in process
General and Administrative Expense [Member]
General and Administrative
Arctic Vision Limited.
Arctic Vision Limited [Member]
Arctic Vision Limited
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Number of Shares, Cancelled/Forfeited
Square footage of leased office space.
Area Of Leased Office Space
Area of office leased
Revision of Prior Period, Change in Accounting Principle, Adjustment [Member]
Cumulative effect of accounting change
Document Financial Statement Error Correction [Flag]
CALIFORNIA
CALIFORNIA
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Potential Common Stock Equivalents Excluded from Computation of Diluted Net Loss per Share
Research and development to Related Party
Research and development to Related Party
Research and development to Related Party
City Area Code
City Area Code
Research and Development Arrangement, Contract to Perform for Others, Type [Axis]
Research and Development Arrangement, Contract to Perform for Others, Type
Net Cash Provided by (Used in) Operating Activities [Abstract]
Operating activities
Proceeds from the issuance of shares under an at-the-market sales agreement.
Proceeds From Issuance At The Market
Proceeds from at-the-market sales agreement, net of issuance costs
2025
Twenty Thousand Twenty Six [ Member]
Twenty Thousand Twenty Six [ Member]
First Milestone Proceeds From Royalty Purchase And Sale Agreement
First Milestone Proceeds From Royalty Purchase And Sale Agreement
First Milestone Proceeds From Royalty Purchase And Sale Agreement
Cantor Fitzgerald Co.
Cantor Fitzgerald & Co1 [Member]
Cantor Fitzgerald & Co1 [Member]
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Less: Accumulated depreciation
General and Administrative Expense, Total
General and Administrative Expense
General and administrative
Weighted average shares outstanding - basic
Weighted average shares - basic
Weighted Average Number of Shares Outstanding, Basic
Weighted Average Number of Shares Outstanding, Basic, Total
Deferred Revenue [Domain]
Deferred Revenue
GEORGIA
GEORGIA
Research and Development Arrangement, Contract to Perform for Others, Type [Domain]
Research and Development Arrangement, Contract to Perform for Others, Type
Net Cash Provided by (Used in) Financing Activities [Abstract]
Financing activities
Research and Development Expense, Policy [Policy Text Block]
Research and Development Costs
Maintenance Fee Due 2023
Maintance Fees Operating License Liability Payments Remainder Of Fiscal Year
Maintance Fees Operating License Liability Payments Remainder Of Fiscal Year
Gain on extinguishment of debt
Gain on extinguishment of debt
Gain (Loss) on Extinguishment of Debt
Gain (Loss) on Extinguishment of Debt, Total
Statement [Table]
Statement [Table]
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Summary of Activity Related to Stock Options
Schedule of Related Party Transactions, by Related Party [Table]
Schedule Of Related Party Transactions By Related Party [Table]
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Weighted Average Assumptions Used in Black-Scholes Option Pricing Model to Calculate Fair Value of Underlying Common Stock
Document Fiscal Period Focus
Document Fiscal Period Focus
Lessee, Operating Lease, Liability, to be Paid, Total
Lessee, Operating Lease, Liability, to be Paid
Operating lease liability payments due
Share-Based Payment Arrangement, Option, Exercise Price Range, Lower Range Limit
Exercise Price Lower Range Limit
Commitment and Contingencies [Table]
Commitment And Contingencies [Table]
Commitment And Contingencies [Table]
Restricted Cash, Statement of Financial Position [Extensible Enumeration]
Restricted Cash, Statement of Financial Position [Extensible Enumeration]
Related Party Transactions Disclosure [Text Block]
Summary of Related Party Transactions Disclosure
Issuance of common shares under at-the-market sales agreement, shares
Stock issued during period shares at market sales agreement.
Stock Issued During Period Shares At Market Sales Agreement
Accrued Professional Fees, Current
Accrued professional fees
Statement [Line Items]
Statement [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Antidilutive securities excluded from computation of earnings per share
2023
Twenty Thousand Twenty Three [ Member]
Twenty Thousand Twenty Three [ Member]
Machinery and Equipment [Member]
Machinery and Equipment
2027
Twenty Thousand Twenty Eight [ Member]
Twenty Thousand Twenty Eight [ Member]
Exercise Price Range [Domain]
Exercise Price Range
Warrant [Member]
Stock Purchase Warrants
Entity incorporation date
Entity Incorporation, Date of Incorporation
Asset Class [Domain]
Asset Class
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Schedule of Net Deferred Tax Assets
Accounts receivable
Accounts Receivable, after Allowance for Credit Loss, Current
Accounts Receivable, after Allowance for Credit Loss, Current, Total
Cumulative Effect, Period of Adoption [Domain]
Cumulative Effect, Period of Adoption
Common Stock [Member]
Common Stock
Debt Instrument [Line Items]
Debt Instrument [Line Items]
Net Proceeds From Issuance Of Stock
Net Proceeds From Issuance Of Stocks
Net Proceeds From Issuance Of Stock
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalents, at Carrying Value
Cash and cash equivalents
Cash and cash equivalents
Cash and cash equivalents
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Summary of Share-based Compensation Expense
Royalty Agreement Terms [Member]
Other Assets, Current
Other current assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Aggregate Intrinsic Value
Total
Maintenance Fee Payments Due
Maintenance Fee Payments Due
Prepaid Expense, Current, Total
Prepaid Expense, Current
Prepaid expenses
2011 Plan.
Two Thousand Eleven Stock Incentive Plan [Member]
2011 Stock Incentive Plan
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name
Effective Income Tax Rate Reconciliation, Prior Year Income Taxes, Percent
ASC 740-10
Cover
Cover [Abstract]
Balance at December 31, 2023
Liabilities Related To The Sales Of Future Royalties
Liabilities Related To The Sales Of Future Royalties
Liability related to the sales of future royalties, net
Document Fiscal Year Focus
Document Fiscal Year Focus
Proceeds from Loan
Proceeds from Loan Originations
Debtor-in-Possession Financing, Interest Rate on Borrowings Outstanding
Interest rate on outstanding principal amount
Operating leases rent expense minimum rentals per month.
Operating Leases Rent Expense Minimum Rentals Per Month
Minimum monthly lease payments
Debt Instrument, Periodic Payment, Principal
Debt instrument, principal balance payment
Sale of Stock [Domain]
Sale of Stock
Range two.
Range Two [Member]
$3.00 - $6.99
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Granted
Income tax disclosure table.
Income Tax Disclosure [Table]
Income Tax Disclosure [Table]
Security Exchange Name
Security Exchange Name
Upfront payments received.
Upfront Payments Received
Upfront payment received
Domestic Tax Authority [Member]
Federal
New Accounting Pronouncements, Policy [Policy Text Block]
Recent Accounting Pronouncements
Initial proceeds from royalty sale and purchase agreement net of certain expenses.
Initial Proceeds From Royalty Sale and Purchase Agreement Net of Certain Expenses
Initial payment
Preferred Stock, Shares Issued, Total
Preferred Stock, Shares Issued
Preferred stock, shares issued
Preferred Stock, Shares Authorized
Preferred stock, shares authorized
Additional fees for expansion to existing license.
Additional fees for expansion to existing license
Property, Plant and Equipment, Gross, Ending Balance
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Total
Property, Plant and Equipment, Gross
Total property and equipment
Effective Income Tax Rate Reconciliation, Change in Enacted Tax Rate, Percent
Impact of federal rate change
Clinical And Regulatory Milestone Payments
Clinical And Regulatory Milestone Payments
Proceeds from royalty purchase and sale agreement, net of $1,862 of issuance costs
Proceeds from royalty purchase and sale agreement, net of issuance costs
Proceeds from royalty purchase and sale agreement, net of issuance costs
Proceeds from royalty purchase and sale agreement
Proceeds from royalty purchase and sale agreement, net of issuance costs
Maintenance Fee Due 2024
2024
Maintenance Fee Payments Due Next Rolling Twelve Months
Maintenance Fee Payments Due Next Rolling Twelve Months
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Weighted Average Exercise Price, Cancelled/Forfeited
Maintenance Fee Due 2028
2028
Maintenance Fee Payments Due In Rolling Year Five
Maintenance Fee Payments Due In Rolling Year Five
Financial Instrument [Axis]
Class of Warrant or Right [Table]
Class Of Warrant Or Right [Table]
Stock Issued During Period, Value, Stock Options Exercised
Exercise of stock options
Entity Emerging Growth Company
Entity Emerging Growth Company
Amendment Flag
Amendment Flag
Schedule of Accrued Liabilities [Table Text Block]
Schedule of Accrued Liabilities
Royalty Purchase and Sale Agreement Text Block
Royalty Purchase and Sale Agreement Text Block
Royalty Purchase and Sale Agreement
Maintenance Fee Due 2027
Maintenance Fee Operating License Liability Payments Due Year Four
Maintenance Fee Operating License Liability Payments Due Year Four
Issuance of common shares under a direct registered offering, shares
Issuance of common shares under a direct registered offering, Shares
Issuance of common shares under a direct registered offering, Shares
Employee stock purchase plan payroll deduction as percentage of regular employee earnings maximum.
Employee Stock Purchase Plan Payroll Deduction As Percentage Of Regular Employee Earnings Maximum
Employee payroll deductions, percent
Basis of Accounting, Policy [Policy Text Block]
Basis of Presentation
Adjustment to prior year tax provision
Adjustment to prior year tax provision
Shares, Issued, Ending Balance
Shares, Issued, Beginning Balance
Shares, Issued
Shares, issued
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right
Number of stock that can be purchased by each warrant
Tax Period [Domain]
Tax Period
Entity File Number
Entity File Number
Gerresheimer regensburg GmbH.
Gerresheimer Regensburg Gmb H [Member]
Gerresheimer Regensburg GmbH
Warrants expiration term.
Warrants Expiration Term
Warrants expiration term
Warrant exercisable date
Class of Warrant or Right, Date from which Warrants or Rights Exercisable
Schedule of operating leases assets and liabilities.
Schedule Of Operating Leases Assets And Liabilities
Operating Leases Included on the Balance Sheet
Global sales amount
Global Sales Amount
Global Sales Amount
Pre-Launch Milestone Payments.
Pre Launch Milestone Payments
Pre-launch milestone payments
Initial Term of Agreement.
Initial Term Of Agreement
Initial term of agreement
Short-Term Debt [Line Items]
Short Term Debt [Line Items]
2025
Lessee, Operating Lease, Liability, to be Paid, Rolling Year Two
First amended and restated loan and security agreement.
First Amended And Restated Loan And Security Agreement [Member]
First Amended and Restated Loan and Security Agreement
Milestone payments received.
Milestone Payments Received
Milestone payments received
Share-Based Payment Arrangement [Abstract]
2024
Twenty Thousand Twenty Five [ Member]
Twenty Thousand Twenty Five [ Member]
Schedule of Annual Maintenance Fee Payments
Schedule of Annual Maintenance Fee Payments [Table Text Block]
Schedule of Annual Maintenance Fee Payments [Table Text Block]
Accounts Payable
Accounts payable (includes $331 to a related party as of December 31, 2023)
Accounts Payable, Current, Total
Accounts Payable, Current
Debt Instrument [Axis]
Debt Instrument
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Non-vested units outstanding, Weighted Average Grant Date Fair Value, Ending balance
Non-vested units outstanding, Weighted Average Grant Date Fair Value, Beginning balance
Deferred Tax Assets, Valuation Allowance, Total
Deferred Tax Assets, Valuation Allowance
Deferred tax assets, valuation allowance
Valuation allowance
Deferred tax assets, valuation allowance
Share-Based Payment Arrangement, Option, Exercise Price Range, Upper Range Limit
Exercise Price Upper Range Limit
Operating Expenses
Total operating expenses
Auditor Location
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Expected term (years)
Entity Address, Address Line Two
Entity Address, Address Line Two
Preferred stock, $0.001 par value; 10,000,000 shares authorized and no shares issued at December 31, 2023 and 2022
Preferred Stock, Value, Issued, Ending Balance
Preferred Stock, Value, Issued, Beginning Balance
Preferred Stock, Value, Issued, Total
Preferred Stock, Value, Issued
Entity Small Business
Entity Small Business
Entity Shell Company
Entity Shell Company
Number of Operating Segments
Number of operating segments
Schedule of Nonvested Share Activity [Table Text Block]
Summary of the Activity Related to RSUs
Title of Individual [Axis]
Sale of Stock, Number of Shares Issued in Transaction
Number of shares sold under facility
Class of Warrant or Right, Exercise Price of Warrants or Rights
Class of warrant Exercise
Upfront payment member.
Upfront Payment [Member]
Upfront Payment
Total minimum lease payments
Total minimum lease payments
Operating Leases Future Minimum Payment Due
Operating Leases Future Minimum Payment Due
Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Unrecognized compensation expense related to the RSUs
Computer Equipment [Member]
Computer Equipment
Net Income (Loss) Per Share
Earnings Per Share [Text Block]
Arctic Vision Limited [Member]
Arctic Visions Limited [Member]
Arctic Vision Limited
Entity Address, Address Line One
Entity Address, Address Line One
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Antidilutive Securities [Axis]
Antidilutive Securities
Restricted cash ($100 as of December 31, 2021 is recorded in other current assets)
Restricted cash ($100 as of December 31, 2021 is recorded in other current assets)
Restricted Cash, Total
Restricted Cash
Restricted cash ($160 and $100 as of December 31, 2022 and 2021, respectively, is recorded in other current assets)
Subsequent Event Type [Domain]
Subsequent Event Type
Debt Instrument, Unused Borrowing Capacity, Description
Line of credit facility, remaining borrowing capacity description
Letter Agreement
Letter Agreement [Member]
Letter Agreement [Member]
Manufacturing Supply Agreement Member.
Manufacturing Supply Agreement [Member]
Manufacturing Supply Agreement
Income Statement Location [Axis]
Income Statement Location
Variable Lease, Cost
Variable Lease, Cost
Deferred tax assets lease liability.
Deferred Tax Assets Lease Liability
Lease liability
Exercise Price Range [Axis]
Exercise Price Range
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Expected dividend yield
Development milestone payments.
Development Milestone Payments
Development milestone payments
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net loss
Net (loss) income
Line of Credit Facility, Lender [Domain]
Line of Credit Facility, Lender
Fair Value, Inputs, Level 2 [Member]
Level 2
Share Price
Purchase price per share
Schedule of Unrecognized Tax Benefits, Excluding Amounts Pertaining to Examined Tax Returns Roll Forward [Table Text Block]
Summary of Activity Related to Uncertain Tax Positions
Product and Service [Axis]
Product and Service
Title of 12(b) Security
Title of 12(b) Security
Amount of upfront payment and development milestones payment to be received under license agreement.
Amount Of Upfront Payment And Development Milestones Payment To Be Received Under License Agreement
Amount of upfront payment and development milestones payment to be received under license agreement
Proceeds from registered direct offering
Proceeds From Registered Direct Offering
Proceeds From Registered Direct Offering
Purchase price of share and warrant
Purchase Price Of Share And Warrant
Purchase Price Of Share And Warrant
Consideration received from expansion of business
Business Combination, Contingent Consideration, Asset
Business Combination, Contingent Consideration, Asset, Total
Net Cash Provided by (Used in) Investing Activities [Abstract]
Investing activities
State and Local Jurisdiction [Member]
State
Segment Reporting, Policy [Policy Text Block]
Segment Information
Weighted Average Number of Shares Outstanding, Diluted, Adjustment
Weighted Average Number Diluted Shares Outstanding Adjustment, Total
Long-Lived Tangible Asset [Domain]
Long-Lived Tangible Asset
Gross decreases - settlements with taxing authorities
Gross decreases - settlements with taxing authorities
Unrecognized Tax Benefits, Decrease Resulting from Settlements with Taxing Authorities
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
Restricted Cash
Warrant expiration date
Warrant Expiration Date
Warrant Expiration Date
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding
Common stock, shares outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Risk-free interest rate
Share-Based Payment Arrangement [Text Block]
Share-Based Compensation
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Forfeited
Accrued Royalties, Current
Deferred tax liabilities right of use assets.
Deferred Tax Liabilities Right Of Use Assets
Right-of-use asset
Fair Value Measurements, Recurring and Nonrecurring [Table Text Block]
Summary of Assets and Liabilities Measured at Fair Value
Reconciliation of Unrecognized Tax Benefits, Excluding Amounts Pertaining to Examined Tax Returns [Roll Forward]
Summary of activity related to uncertain tax positions
Income Statement Location [Domain]
Income Statement Location
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Weighted Average Exercise Price, Granted
Share-Based Payment Arrangement, Option and Stock Appreciation Rights, Activity [Table Text Block]
Additional Information about the Stock Option Outstanding and Exercisable
Document Type
Document Type
Unrecognized Tax Benefits, Income Tax Penalties Expense
Unrecognized tax benefits, income tax penalties expense
Net Cash Provided by (Used in) Investing Activities
Net cash used in investing activities
Maintenance Fee Due 2027
2027
Maintenance Fee Payments Due In Rolling Year Four
Maintenance Fee Payments Due In Rolling Year Four
Counterparty Name [Domain]
Counterparty Name
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Number of Shares, Forfeited
Common stock shares aggregate offering price
Common stock,aggregate offering price
Common stock,aggregate offering price
Net Cash Provided by (Used in) Financing Activities
Net cash provided by financing activities
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized
Increase in common stock for future issuance, shares
Royalty Purchases And Sale Agreement
Royalty Purchases And Sale Agreement
Royalty Purchase And Sale Agreement
Maintenance Fee Due 2023
2023
Maintenance Fee Payments Remainder Of Fiscal Year
Maintenance Fee Payments Remainder Of Fiscal Year
Entity Filer Category
Entity Filer Category
Deferred Tax Assets, Tax Credit Carryforwards, Research
Deferred tax Federal Research and Development credit
Debt Instrument, Periodic Payment, Interest
Debt Instrument, Final Payment, Interest
Accrued severance costs.
Accrued Severance Costs
Accrued severance
Restricted cash in other current assets
Restricted Cash and Cash Equivalents
Restricted Cash and Cash Equivalents, Total
Asset Class [Axis]
Asset Class
Tax credits
Deferred Tax Assets, Tax Credit Carryforwards, Total
Deferred Tax Assets, Tax Credit Carryforwards
Liabilities
Total liabilities
First cumulative net sales of products.
First Cumulative Net Sales Of Products
First cumulative net sales of products
Property, Plant and Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Debt Instrument, Description of Variable Rate Basis
Debt instrument, description of variable rate basis
Total stockholders' (deficit) equity
Equity, Attributable to Parent
Ending balance
Beginning balance
Renewal Term of Agreement.
Renewal Term Of Agreement
Renewal term of agreement
Documents Incorporated by Reference
Documents Incorporated by Reference [Text Block]
Silicon Valley Bank, MidCap funding III trust and MidCap financial trust.
Silicon Valley Bank Mid Cap Funding I I I Trust And Mid Cap Financial Trust [Member]
Silicon Valley Bank, MidCap Funding III Trust and MidCap Financial Trust
Net income (loss) - basic and diluted
Net Income (Loss)
Net (loss) income
Net income (loss)
Operating Lease Imputed interest.
Operating Lease Imputed Interest
Less imputed interest
Schedule of Research and Development Arrangement, Contract to Perform for Others [Table]
Schedule Of Research And Development Arrangement Contract To Perform For Others [Table]
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
State tax rate
Award Date [Axis]
Non-cash interest expense on liability related to the sales of future royalties, net of issuance costs accretion
Non-cash interest expense on liability related to the sales of future royalites
Non-cash interest expense on liability related to the sales of future royalites
Non-cash interest expense
Statement of Financial Position [Abstract]
Stock Options [Member]
Stock Options [Member]
Weighted average shares outstanding - diluted
Weighted Average Number of Shares Outstanding, Diluted
Weighted Average Number of Shares Outstanding, Diluted, Total
Non vested restricted stock units.
Non Vested Restricted Stock Units [Member]
Non-vested Restricted Stock Units
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Schedule of Statutory and Effective Income Tax Rate Reconciliation
Credit Facility [Axis]
Credit Facility
Asset Acquisition [Domain]
Shares Issued, Price Per Share
Shares issued, price per share
Effective Income Tax Rate Reconciliation, Percent
Total income tax provision (benefit)
Maintenance Fee Due 2025
Maintenance Fee Operating license Liability Payments Due Year Two
Maintenance Fee Operating license Liability Payments Due Year Two
Other
Effective Income Tax Rate Reconciliation, Deduction, Other, Percent
License and other revenue from Related Party
License and other revenue from Related Party
License and other revenue from Related Party
2026
Lessee, Operating Lease, Liability, to be Paid, Rolling Year Three
Operating Lease, Weighted Average Remaining Lease Term
Operating lease, remaining lease term
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Income Tax Disclosure [Text Block]
Income Taxes
Aura
Aura [Member]
Aura [Member]
Share based compensation arrangement by share based payment award increase in number of shares reserved for issuance percentage.
Share Based Compensation Arrangement By Share Based Payment Award Increase In Number Of Shares Reserved For Issuance Percentage
Annual increase of common stock reserved for issuance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Weighted Average Exercise Price, Options outstanding, Ending balance
Weighted Average Exercise Price, Options outstanding, Beginning balance
Weighted average exercise price
Weighted Average Exercise Price
Schedule of Earnings Per Share, Basic and Diluted
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Leasehold Improvements [Member]
Leasehold Improvements
Income Tax Authority [Axis]
Income Tax Authority
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Fair Value Disclosures [Abstract]
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV
Payments to Acquire Property, Plant, and Equipment, Total
Payments to Acquire Property, Plant, and Equipment
Acquisition of property and equipment
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Number of Shares, Vested
Issuance of common shares under private placement, shares
Stock Issued During Period, Shares, New Issues
Purchase of common stock by institutional purchasers
Employee-related Liabilities, Current, Total
Employee-related Liabilities, Current
Accrued employee costs
Second Milestone Proceeds From Royalty Purchase And Sale Agreement
Second Milestone Proceeds From Royalty Purchase And Sale Agreement
Second Milestone Proceeds From Royalty Purchase And Sale Agreement
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations
Cash, cash equivalents and restricted cash, end of period
Cash, cash equivalents and restricted cash, beginning of period
Cash, cash equivalents and restricted cash at end of period
Cash, cash equivalents and restricted cash at end of period
Deferred Revenue, Current, Total
Deferred Revenue, Current
Deferred revenue
Income Tax Disclosure [Abstract]
Finite-Lived Intangible Assets by Major Class [Axis]
Second amended and restated loan and security agreement.
Second Amended And Restated Loan And Security Agreement [Member]
Second Amended and Restated Loan and Security Agreement
In May 2023
In May Two Thousand Twenty Three [member]
In May Two Thousand Twenty Three [member]
Initial proceeds from royalty purchase and sales agreement net of certain expenses.
Initial Proceeds From Royalty Purchase and Sales Agreement Net of Certain Expenses
Initial proceeds from royalty purchase and sales agreement net of certain expenses
Operating Loss Carryforwards, Total
Operating Loss Carryforwards
Net operating loss carryforwards