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100010 - Statement - Balance Sheets
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100030 - Statement - Statements of Operations and Comprehensive Loss
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100050 - Statement - Statements of Cash Flows
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100060 - Disclosure - The Company
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100070 - Disclosure - Significant Accounting Policies
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100080 - Disclosure - Property and Equipment, Net
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100090 - Disclosure - Accrued Liabilities
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100100 - Disclosure - Long-Term Debt
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100110 - Disclosure - Convertible Shareholder Notes Payable
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100120 - Disclosure - Convertible Preferred Stock
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100130 - Disclosure - Common Stock
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100140 - Disclosure - Stock Purchase Warrants
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100150 - Disclosure - Share-Based Compensation
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100160 - Disclosure - Income Taxes
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100170 - Disclosure - Commitment and Contingencies
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100180 - Disclosure - License Agreements
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100190 - Disclosure - Collaborative Agreement
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100200 - Disclosure - Available-for Sale Investments
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100210 - Disclosure - Fair Value Measurements
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100220 - Disclosure - Net Loss per Share
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100230 - Disclosure - Quarterly Financial Information (Unaudited)
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100240 - Disclosure - Subsequent Events
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100250 - Disclosure - Significant Accounting Policies (Policies)
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100300 - Disclosure - Share-based compensation (Tables)
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100340 - Disclosure - Fair Value Measurements (Tables)
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100350 - Disclosure - Net Loss per Share (Tables)
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100360 - Disclosure - Quarterly Financial Information (Unaudited) (Tables)
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100370 - Disclosure - The Company - Additional Information (Detail)
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100380 - Disclosure - Significant Accounting Policies - Additional Information (Detail)
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100390 - Disclosure - Property and Equipment, Net - Schedule of Property and Equipment, Net (Details)
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100400 - Disclosure - Accrued Liabilities - Schedule of Accrued Liabilities (Detail)
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100410 - Disclosure - Long-Term Debt - Additional Information (Details)
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100420 - Disclosure - Long-Term Debt - Scheduled Payments for Loan Agreement (Details)
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100430 - Disclosure - Convertible Shareholder Notes Payable (Detail)
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100450 - Disclosure - Convertible Preferred Stock (Detail)
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100460 - Disclosure - Convertible Preferred Stock (Parenthetical) (Detail)
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100470 - Disclosure - Common Stock - Additional Information (Detail)
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100480 - Disclosure - Stock Purchase Warrants - Additional Information (Details)
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100490 - Disclosure - Share-Based Compensation - Additional Information (Details)
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100500 - Disclosure - Share-Based Compensation - Summary of Share-based Compensation Expense (Details)
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100510 - Disclosure - Share-Based Compensation - Weighted Average Assumptions Used in Fair Value Calculation for Underlying Common Stock (Details)
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100520 - Disclosure - Share-Based Compensation - Summary of Activity Related to Stock Options (Details)
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100530 - Disclosure - Share-Based Compensation - Additional Information about the Stock Option Outstanding and Exercisable (Details)
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100540 - Disclosure - Income Tax - Additional Information (Detail)
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100550 - Disclosure - Schedule of Net Deferred Tax Assets (Detail)
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100560 - Disclosure - Schedule of Statutory and Effective Income Tax Rate Reconciliation (Detail)
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100570 - Disclosure - Commitment and Contingencies - Additional Information (Details)
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100580 - Disclosure - Commitment and Contingencies - Future Minimum Commitments Due Under Non-Cancelable Operating Leases (Details)
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100590 - Disclosure - License Agreements - Additional Information (Detail)
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100600 - Disclosure - Collaborative Agreement - Additional Information (Details)
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100610 - Disclosure - Available-for Sale Investments- Summary of Company's Available-For-Sale Investments (Details)
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100620 - Disclosure - Fair Value Measurements - Additional Information (Detail)
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100630 - Disclosure - Fair Value Measurements - Summary of Assets and Liabilities Measured at Fair Value (Detail)
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100640 - Disclosure - Fair Value Measurements - Summarizes the Changes in Fair Value of the Level 3 Liability, Stock Purchase Warrants (Detail)
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100650 - Disclosure - Net Loss Per Share - Potential Common Stock Equivalents Excluded from Computation of Diluted Net Loss per Share (Details)
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100660 - Disclosure - Quarterly Financial Information (Unaudited) - Summary of Quarterly Financial Information - (Details)
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100670 - Disclosure - Subsequent Events - Additional Information (Detail)
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